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  Product Name 3-Ethoxy-4-[(2-hydroxyethyl)amino]-3-cyclobuten-1,2-dione  
 
 graphch/SQ001.gif  
 
Product Specifications 
 
 catalogue no.SQ001 
 chemical name3-Ethoxy-4-[(2-hydroxyethyl)amino]-3-cyclobuten-1,2-dione 
 IUPAC name3-ethoxy-4-[(2-hydroxyethyl)amino]cyclobut-3-ene-1,2-
dione
 
 molecular formulaC8H11O4 
 molecular weight [g/mol]185.18  
 CAS131588-93-7 
 purity97%+ 
 categorySquaric Acid Derivatives 
 melting pointn.d. 
 boiling pointn.d. 
 appearancecolourless liquid 
 solubilityMeOH 
 shipping temperatureambient 
 long term storage4oC 
 Spectra1-H NMR 
 NMR analytics500 MHz (d6-DMSO) 
 special commentssensitive to hydrolysis 
 
 Safety Information 
 
 R-sentenceR: 36/37/38 
 S-sentenceS: 26, 37/39 
 hazardous substance symbolXn 
 safety infoCaution, substance not fully tested. Potential health effects. 
 
 References 1. Tietze, L.F., Arlt, M., Beller, M., Glüsenkamp, K.-H., Jähde, E., Rajewsky, M.F.: Squaric acid diethylester: a new coupling reagent for the formation of drug biopolymer conjugates. Synthesis of squaric acid ester amides and diamide. Chem. Ber. 124, 1215-1221, 1991.

2. Glüsenkamp, K.-H., Drosdziok, W., Eberle, G., Jähde, E., Rajewsky, M.F.: Squaric acid diethylester: A simple and convenient coupling reagent. Z. Naturforsch. 46c, 498-501, 1991
 
 
 Patents  
   United States Patent: Method for Immobilizing biomolecules and affinity ligands on polymer carriers. Karl-Heinz Glüsenkamp et. Al., US 6,602,692 B1, Aug. 2003 
 
 Application Notes  
  reactive intermediate 
 
 Ordering Information  
 
 
Cat. No. | Product Name | Quantity | Price  
 
SQ001.1   3-Ethoxy-4-[(2-hydroxyethyl)amino]-3-cyclobuten-1,2-dione   0.05 g   129,- €  
SQ001.2   3-Ethoxy-4-[(2-hydroxyethyl)amino]-3-cyclobuten-1,2-dione   0.25 g   389,- €  
 
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